I personally am looking forward to Supernatural and Chuck. The Lucifer storyline sounds like it'll be amazing (and he's played by the same guy as Jacob in lost). I love the way Chuck mixes in comedy as well, I think it's hilarious .
Personally Lost has been getting extremely weird (nuke going off, Jacob dying like a twig, wtf?), and I've been losing interest in it, even though it was one of my favorite shows before.