I was skeptical about the San Andreas thing too at first. But I just recently learned that the three cities in the original GTA (which I never played) were Portland, Vice City, and San Andreas. Now since they've made an entire game based in Portland and another one in Vice City, it stands to reason that the next game will in fact be set in San Andreas. As for Las Vegas, I think that was just a rumor. It really doesn't make sense since they are always set in fictional cities and Las Vegas is a real place (well, almost ).
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