This has been discussed many times. As usual, everyone has their own oppinion. I'll throw in my 2 cents:
I set up tests with several different computers, each running a different AV and loading them with infected files. I tested Norton, Symantec, TrendMicro, AVG Free, ZoneAlarm with AV & Spyware, NOD32, and Avira AntiVir.
Norton & Symantec were the worste and found almost none of my infected files. Avira AntiVir (free version) was the best and found 100% of them, AVG was second best and found most but not all Virii.
ZoneAlarm was very good at finding Spyware, but not so good at finding Virii.
After all my testing and from personal experience, my preference is Avira AntiVir. Best of all, it's free
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