Have to add:
Matt Bellamy (Muse) - as has been mentioned, he has got a huge ego etc. but he is very competant, and most people I know can tell when a Muse song is on the radio.
Nick McCabe (The Verve) - they are no longer together and all that, but he definitely had a unique style. overall he is still my favourite guitarist - that isn't to say I think he is THE BEST, of course - Page, Hendrix, etc.
Nick Drake (for acoustic/finger picking playing) - Santana is an amazing classical player, Jimmy Page was great on the acoustic too, and John Martyn, etc... but Nick Drake had the most unique acoustic sound in my opinion