Some people indeed say formatting and doing a clean OS reinstall once a year is unavoidable, but I've been using the same one since 2007 (and only because I had a virus attack back then) and it still feels as fast as always.
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CCleaner
I just use cclearner and your! uninstaller to uninstal apps
CCleaner >> all and Ghost image my clean windows after format c:
TuneUp Utilities
Ccleaner is very usefull ..
for me CCleaner only
I'm using Tuneup utilities, Ccleaner, Ashampoo HDD control & Perfect uninstaller.
Glary Ultities
my favorite is CCleaner!