I'd go with those two, or possibly comodo.
I run Avira on one laptop, avast (+ the comodo firewall) on my stationary machine, and the whole comodo package on two other laptops.
Avast seems the heaviest on resources, while Avira has annoying popups on updates. Comodo can be a bit tricky to get into (mainly the firewall), but it's got a few options I like, and the firewall + antivirus combination is pretty smooth if you're looking for something quick and easy. (Using both fw and av from the same vendor might not be optimal, though.) But their defense+ component I generally turn off.
This is cool as a second opinion type scanner you can bring with you on a usb stick.
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