A large cache is very recommendable with that connection speed, if you have a lot of RAM. It makes sense that the torrents freeze, sometimes for a sizable amount of time, as the data is actually written to the disk. It's either that or putting more pressure on the hard drive by writing semi-constantly.
If you want to do something about it, you can tick "reduce memory usage when the cache is not needed" and "write out finished pieces immediately". They may reduce the amount of time torrents are frozen for at the cost of increasing disk writes somewhat.
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